Measurement of invasive blood pressure in rats

Parasuraman, Subramani; Raveendran, Ramasamy

doi:10.4103/0976-500X.95521

MethodsArchivesVol. 1 | Issue 2 | 2010 | pp. 87–93Open Access

Measurement of invasive blood pressure in rats

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¹Department of Pharmacology, Jawaharlal Institute of Postgradute Medical Education and Research, Pondicherry, India ABSTRACT Blood pressure (BP) is one of the vital parameters used to assess the cardiovascular functions of a mammal. BP is commonly recorded using invasive, noninvasive, and radio telemetry methods, but invasive blood pressure (IBP) recording is considered the gold standard. IBP provides a direct indication of the effect of the investigational products on the circulatory system. Recording the IBP in rodents is an essential part of the preliminary screening of any product to determine its effect on the cardiovascular system. The present article describes the measurement of the IBP in Wistar rats/Sprague Dawley rats. Key words: Carotid artery, invasive blood pressure, tracheostomy.

Correspondence: Subramani Parasuraman
Department of Pharmacology, Jawaharlal Institute of Postgradute Medical Education and Research, Pondicherry, India ABSTRACT Blood pressure (BP) is one of the vital parameters used to assess the cardiovascular functions of a mammal. BP is commonly recorded using invasive, noninvasive, and radio telemetry methods, but invasive blood pressure (IBP) recording is considered the gold standard. IBP provides a direct indication of the effect of the investigational products on the circulatory system. Recording the IBP in rodents is an essential part of the preliminary screening of any product to determine its effect on the cardiovascular system. The present article describes the measurement of the IBP in Wistar rats/Sprague Dawley rats. Key words: Carotid artery, invasive blood pressure, tracheostomy.
Email: parasuphd@gmail.com

Published: Jan 1, 2010

DOI: https://doi.org/10.4103/0976-500X.95521
Article URL: https://front-journal-woad.vercel.app/article/j-pharmacol-pharmacother-3-2-172
PDF URL: https://front-journal-woad.vercel.app/article/j-pharmacol-pharmacother-3-2-172.pdf

Abstract

Blood pressure (BP) is one of the vital parameters used to assess the cardiovascular functions of a mammal. BP is commonly recorded using invasive, noninvasive, and radio telemetry methods, but invasive blood pressure (IBP) recording is considered the gold standard. IBP provides a direct indication of the effect of the investigational products on the circulatory system. Recording the IBP in rodents is an essential part of the preliminary screening of any product to determine its effect on the cardiovascular system. The present article describes the measurement of the IBP in Wistar rats/Sprague Dawley rats.

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