Open access · Peer reviewed · Scopus journal
Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy
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- 1Department of Ophthalmology, Surat Municipal Institute of Medical Education and Research, Surat, Indian Institute of Public Health, Gandhinagar, India Research Paper.
Published in Journal of Pharmacology and Pharmacotherapeutics
Correspondence: Deepika Singhal
Department of Ophthalmology, Surat Municipal Institute of Medical Education and Research, Surat, Indian Institute of Public Health, Gandhinagar, India Research Paper.
Copyright: © 2011 The Author(s). This is an open access article.
Abstract
Objective: To study the effect of brimonidine on intraocular pressure (IOP) following capsulotomy among Indian subjects. Materials and Methods: The study was a nonrandomized trial with open label. Results: 80% of the subjects showed a decrease in IOP after instilling 0.2% brimonidine (1 hour pre capsulotomy). No such decrease was observed in control. After 1 and 4 h post capsulotomy a statistically signifi cant decrease in IOP ranging between 1–10 mmHg was found in 73.3% of the treatment group. Conclusions: In the present study 0.2% brimonidine has been proven effective to counteract the increase in IOP following Nd-YAG laser capsulotomy in Indian setting.
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